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Life Threatening? No
Write-up: Patient presents in fulminant liver failure. Per GI team documentation: "We do not have an etiology for this acute liver injury. The differential diagnosis includes drug-induced liver injury, acute viral hepatitis, ischemic hepatitis, autoimmune hepatitis and indeterminate. Acetaminophen and salicylate levels are negative. Alcohol level is negative. Although patient does abuse alcohol on a daily basis, her presentation is not consistent with acute alcoholic hepatitis. Serologies have been sent to evaluate the differential diagnosis and other potential causes of acute liver injury. Liver imaging including Doppler ultrasound does not reveal any abnormality and there is no evidence of chronic liver disease." We have found four case reports of hepatitis/autoimmune hepatitis related to mRNA vaccines. We have additionally had a case of fulminant liver failure in our community a few months back of which no other etiology was identified other then mRNA vaccine. Because of such, and with no other identifiable cause, we are concerned her acute sudden liver failure was vaccine induced.
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